Products
Trimethoprim
Trimethoprim is a bacteriostatic antibiotic used mainly in the prophylaxis and treatment of urinary tract infections.Target: DHFRTrimethoprim (TMP), an inhibitor of dihydrofolate reductase, decreases the level of tetrahydrofolate supplying one-carbon units for biosynthesis of nucleotides, proteins, and panthotenate. TMP caused induction of DnaK, DnaJ, GroEL, ClpB, and IbpA/B Hsps. Among these Hsps, IbpA/B were most efficiently induced by TMP and coaggregated with the insoluble proteins
Density:
1.252
Boiling Point:
526 oC at 760 mmHg
Melting Point:
199-203℃
Flash Point:
271.9 oC
Storage Temperature:
2-8°C
Refractive index:
1.6000 (estimate)
Solubility:
DMSO: soluble <0.1 g/100 mL at 24 oC
Stability:
Stable. Incompatible with strong oxidizing agents, acids.
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