White SolidEplerenone derives its antihypertensive effect by blocking the binding of aldosteroneat the mineralocorticoid receptor (MR). The drug, which was previously approvedonly for the oral treatment of hypertension, is now indicated to improve survival ofstable patients with left ventricular systolic dysfunction (ejection fraction ＜40%) andclinical evidence congestive heart failure (CHF) after an acute myocardial infarction.

Density:

1.31

Boiling Point:

597.9°Cat760mmHg

Melting Point:

241-243oC

Flash Point:

259.5°C

Alpha:

D +5° (c = 0.437 in chloroform)

Storage Temperature:

Store at RT

Refractive index:

1.587

Solubility:

DMSO: soluble2mg/mL, clear (warmed)