Ciclesonide(RPR251526) is a glucocorticoid used to treat obstructive airway diseases.Target: Glucocorticoid ReceptorCiclesonide (CIC) is an inhaled glucocorticosteroid. CIC (5 microM) was rapidly hydrolyzed by NHBE cells (approximately 30% conversion at 4h), with almost complete conversion by 24h. In liver and NHBE cells, major involvement of cytosolic carboxylesterases, with some contribution by cholinesterases, was indicated. The highest level of conversion was found in the liver, 

Density:

1.23 g/cm3

Boiling Point:

665ºC at 760 mmHg

Melting Point:

209-211 °C

Flash Point:

210ºC

Storage Temperature:

Sealed in dry,2-8°C

Refractive index:

1.575